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Rabbit Anti-CRMP5 /BF555 Conjugated antibody (bs-23954R-BF555)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-23954R-BF555
英文名稱 Rabbit Anti-CRMP5 /BF555 Conjugated antibody
中文名稱 BF555標記的二氫嘧啶酶相關蛋白5抗體
別    名 Collapsin response mediator protein 5; CRAM; CRMP 3 associated molecule; CRMP 5; CRMP3 associated molecule; Dihydropyrimidinase like 5; Dihydropyrimidinase related protein 5; DPYS L5; DPYSL 5; DPYSL5; DRP 5; DRP5; FLJ45383; Ulip 6; Ulip6; ULIP6 protein.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  細胞生物  免疫學  神經生物學  細胞類型標志物  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 65kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CRMP5
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
The collapsin response mediator protein (CRMP) family of proteins (also referred to as ULIP6) are a group of neurologic proteins that have been found to play key roles in growth cone guidance during neural development. CRMP5 has relatively low sequence homology with the other four members of the CRMP family. CRMP5 is expressed in the developing nervous system in an expression pattern that resembles CRMP2 and has a peak expression during the first postnatal week. Elevated levels of autoantibody to CRMP5 have been shown to be linked paraneoplastic autoimmune optic neuritis and other paraneoplastic neoplasms. Auto-immunity against CRMP5 expression (predominantly the N-terminal epitopes) is also being investigated as an oncological marker in the respiratory system and in the thymus.

Subunit:
Homotetramer, and heterotetramer with other DPYS-like proteins. Interacts with DPYSL2, DPYSL3 and DPYSL4.

Subcellular Location:
Cytoplasm.

Similarity:
Belongs to the DHOase family. Hydantoinase/dihydropyrimidinase subfamily.

Database links:

Entrez Gene: 56896 Human

Entrez Gene: 65254 Mouse

Entrez Gene: 100910964 Rat

Entrez Gene: 65208 Rat

Omim: 608383 Human

SwissProt: Q9BPU6 Human

SwissProt: Q9EQF6 Mouse

SwissProt: Q9JHU0 Rat

Unigene: 299315 Human

Unigene: 27732 Mouse

Unigene: 44871 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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