97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
97精品视频在线看,2023天天射天天干,女人内精69xxxxx免费软件
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-TRPV1/Cy3 Conjugated antibody (bs-23926R-Cy3)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-23926R-Cy3
英文名稱 Rabbit Anti-TRPV1/Cy3 Conjugated antibody
中文名稱 Cy3標記的辣椒素受體抗體
別    名 Capsaicin receptor; DKFZp434K0220; Osm 9 like TRP channel 1; Osm-9-like TRP channel 1; OTRPC1; Transient receptor potential cation channel subfamily V member 1; TRPV 1; TRPV1; Vanilloid receptor 1; Vanilloid receptor subtype 1; VR 1; VR1; TRPV1_HUMAN.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  心血管  免疫學  細胞凋亡  細胞膜受體  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse,  (predicted: Human, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 92kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human TRPV1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
The detection of noxious stimuli (chemical, mechanical, or thermal) occurs predominantly at the peripheral terminals of primary afferent neurons. This information is ultimately transmitted to the central nervous system to evoke a perception of pain which initiates appropriate protective reflexes. The receptor for capsaicin, VR1 (vanilloid receptor 1; TRPV1 is a nonselective cation channel that resembles members of the transient receptor potential (TRP) family of ion channels. The vanilloid receptor 1 protein functions both as a receptor for capsaicin and a transducter of noxious thermal stimuli. VR1 protein is localized to small-diameter sensory neurons within the dorsal root ganglia and nerve terminals in the dorsal horn.

Function:
Receptor-activated non-selective calcium permeant cation channel involved in detection of noxious chemical and thermal stimuli. Seems to mediate proton influx and may be involved in intracellular acidosis in nociceptive neurons.

Subunit:
Self-associates. Probably homotetramer. May also form a heteromeric channel with TRPV3. Interacts with calmodulin, PIRT, PRKCM and CSK. Interacts with PRKCG and NTRK1, probably by forming a trimeric complex.

Subcellular Location:
Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein (By similarity). Cell projection, dendritic spine membrane; Multi-pass membrane protein.

Tissue Specificity:
Widely expressed at low levels. Expression is elevated in dorsal root ganglia. In skin, expressed in cutaneous sensory nerve fibers, mast cells, epidermal keratinocytes, dermal blood vessels, the inner root sheet and the infundibulum of hair follicles, differentiated sebocytes, sweat gland ducts, and the secretory portion of eccrine sweat glands (at protein level).

Post-translational modifications:
Phosphorylation by PKA reverses capsaicin-induced dephosphorylation at multiple sites, probably including Ser-117 as a major phosphorylation site. Phoshphorylation by CAMKII seems to regulate binding to vanilloids.

Similarity:
Belongs to the transient receptor (TC 1.A.4) family. TrpV subfamily. TRPV1 sub-subfamily.
Contains 6 ANK repeats.

Database links:

Entrez Gene: 7442 Human

Entrez Gene: 193034 Mouse

Entrez Gene: 83810 Rat

Omim: 602076 Human

SwissProt: Q8NER1 Human

SwissProt: Q704Y3 Mouse

SwissProt: O35433 Rat

Unigene: 579217 Human

Unigene: 655380 Human

Unigene: 447485 Mouse

Unigene: 3073 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

辣椒素受體(Vanilloid receptor subtype 1)是機體的一個重要的損傷性感受蛋白,參與了多種生理活動和病理過程,起到對中樞和外周水平疼痛的形成,還可以激活神經纖維末端的辣椒素受體,調節外周血管的舒縮,影響血壓,對缺血心肌起到保護作用; VR1還參與哮喘的發生,調節胃酸的分泌,促進胃腸蠕動。另外,激活辣椒素受體,還可抑制毛干的增殖,近年來發現他介導腫瘤細胞的凋亡。
版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 欧美交换配乱吟粗大 | 亚洲成人福利 | 国产激情无码一区二区三区 | 欧美日韩偷拍一区 | 久久99精品无码一区二区三区 | 人妻夫の上司犯感との中文字幕 | 国产成人午夜福利在线观看者 | 久久一区二区三区精华液介绍 | 中国一级毛片免费看 | 99精品偷拍视频一区二区三区 | 99妻人人做人人爽 | 欧美久久一级特黄毛片 | 人人爽人人爽人人爽人人片av | 亚洲另类色区欧美日韩图片 | 欧美在线播放成人a | 痉挛高潮喷水av无码免费 | 日韩视频一区在线观看 | 强壮的公次次弄得我高潮a片日本 | 国产成人精品日本亚洲第一区 | 久久免费播放视频 | 国精品产品区三区 | 国产成人精品无码一区二区 | 国产成人亚洲第一 | a级黄色片子 | 99热99热99| 国产丝袜一区视频在线观看 | 色妞AV永久一区二区国产AV | 四虎国产精品永久地址99新强 | 中文字幕在线中文 | 亚洲区色情区激情区小说色情书 | 中文字幕亚洲无线码一区女同 | 国产AV无码专区亚洲精品 | 久久夜色精品国产噜噜亚洲AV | 欧美一级淫片免费午夜视频 | 国产一区二区三区四区成男人 | 天天舔天天干 | www.日韩三级| 天天色人人爱 | 日韩99| 天堂在线www资源在线 | 国产偷伦视频片免费视频 |