97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
伊人狠狠色丁香婷婷综合,精品日韩三级,两人视频在线播放免费观看网站
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-PKD2L1/APC Conjugated antibody (bs-23401R-APC)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-23401R-APC
英文名稱 Rabbit Anti-PKD2L1/APC Conjugated antibody
中文名稱 APC標記的多囊腎疾病因子1蛋白抗體
別    名 Polycystin 2 Like 1, Transient Receptor Potential Cation Channel; Transient Receptor Potential Cation Channel, Subfamily P, Member 3; Polycystin-2 Homolog; Polycystin-2L1; Polycystin-L1; Polycystin-L; PKD2L; TRPP3; PKDL; Polycystic Kidney Disease 2-Like 1 Protein; Polycystic Kidney Disease 2-Like 1; PCL; PK2L1_HUMAN;   
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  信號轉導  通道蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, 
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 92kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PKD2L1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.05M PB, pH 7.5.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
This gene encodes a member of the polycystin protein family. The encoded protein contains multiple transmembrane domains, and cytoplasmic N- and C-termini. The protein may be an integral membrane protein involved in cell-cell/matrix interactions. This protein functions as a calcium-regulated nonselective cation channel. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]

Function:
Pore-forming subunit of a ciliary calcium channel that controls calcium concentration within primary cilia without affecting cytoplasmic calcium concentration. Forms a heterodimer with PKD1L1 in primary cilia and forms a calcium-permeant ciliary channel that regulates sonic hedgehog/SHH signaling and GLI2 transcription. May act as a sour taste receptor by forming a calcium channel with PKD1L3 in gustatory cells; however, its contribution to sour taste perception is unclear in vivo and may be indirect.

Subunit:
Homotrimer; trimerization is independent of calcium-binding. Calcium channels are probably composed of 3 subunit of PKD2L1 and 1 subunit of some PKD1 protein (PKD1, PKD1L1, PKD1L2 or PKDL3). Interacts with PKD1. Interacts with PKD1L1; to form ciliary calcium channel. Interacts with PKD1L3, to form putative sour taste receptor. Interacts with RACK1; inhibits the channel activity possibly by impairing localization to the cell membrane.

Subcellular Location:
Cell projection ? cilium membrane; Multi-pass membrane protein

Tissue Specificity:
Expressed in adult heart, skeletal muscle, brain, spleen, testis, retina and liver. According to PubMed:9748274, expressed at high levels in fetal tissues, including kidney and liver, and down-regulated in adult tissues. According to PubMed:10602361, expressed in fetal brain, but not expressed in fetal lung, liver or kidney. Isoform 4 appears to be expressed only in transformed lymphoblasts.

Similarity:
Belongs to the polycystin family.

Database links:

Entrez Gene: 9033 Human

Entrez Gene: 329064 Mouse

SwissProt: Q9P0L9 Human

SwissProt: A2A259 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 一色一伦一区二区三区 | 啪啪网址大全 | 日韩国产在线播放 | 成人免费看吃奶视频网站 | 国外AV无码精品国产精品 | 久久久久久久久99精品情浪 | 国产成人一区二区在线观看 | 91免费视| 91精品在线视频观看 | 国产精品人妻无码一区二区三区 | 暴力调教一区二区三区 | 国产成人a在线视频免 | 国产成人精品日本亚洲一区 | 乱人伦人成品精国产在线 | 国产精品视频区1 | 国产懂色av | 亚洲中文久久精品无码软件 | 97精品在线观看 | 日本高清不卡中文字幕免费 | 在线免费看黄视频 | 无码专区国产精品第一页 | 99久久精品免费看蜜桃的推荐词 | 99精品视频69V精品视频 | 日本高清不卡中文字幕免费 | 日韩中文字幕亚洲欧美 | 精品无码国模私拍视频 | 国产高清不卡一区二区 | 宁安如梦40集免费观看 | 在线一区视频 | 日本韩国三级aⅴ在线观看 日本视频免费 | 在线午夜av | 久久久久国产一级毛片 | 无码少妇高潮喷水A片免费 欧美性xxxx视频 | 亚洲无码专区三区在线观看 | 国产特级毛片aaaaaaa高清 | YY111111少妇影院免费观看 | 日本伊人精品一区二区三区观看方式 | 免费播放av | 黄色大片大毛片 | 韩国av一区二区三区四区 | free性欧美1819护士 |