97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
吃奶做受在线播放,亚洲一区二区二区久久成人婷婷,强奷漂亮雪白丰满少妇av
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-PKD2L1/BF488 Conjugated antibody (bs-23401R-BF488)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-23401R-BF488
英文名稱 Rabbit Anti-PKD2L1/BF488 Conjugated antibody
中文名稱 BF488標記的多囊腎疾病因子1蛋白抗體
別    名 Polycystin 2 Like 1, Transient Receptor Potential Cation Channel; Transient Receptor Potential Cation Channel, Subfamily P, Member 3; Polycystin-2 Homolog; Polycystin-2L1; Polycystin-L1; Polycystin-L; PKD2L; TRPP3; PKDL; Polycystic Kidney Disease 2-Like 1 Protein; Polycystic Kidney Disease 2-Like 1; PCL; PK2L1_HUMAN;   
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  信號轉導  通道蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, 
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 92kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PKD2L1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
This gene encodes a member of the polycystin protein family. The encoded protein contains multiple transmembrane domains, and cytoplasmic N- and C-termini. The protein may be an integral membrane protein involved in cell-cell/matrix interactions. This protein functions as a calcium-regulated nonselective cation channel. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]

Function:
Pore-forming subunit of a ciliary calcium channel that controls calcium concentration within primary cilia without affecting cytoplasmic calcium concentration. Forms a heterodimer with PKD1L1 in primary cilia and forms a calcium-permeant ciliary channel that regulates sonic hedgehog/SHH signaling and GLI2 transcription. May act as a sour taste receptor by forming a calcium channel with PKD1L3 in gustatory cells; however, its contribution to sour taste perception is unclear in vivo and may be indirect.

Subunit:
Homotrimer; trimerization is independent of calcium-binding. Calcium channels are probably composed of 3 subunit of PKD2L1 and 1 subunit of some PKD1 protein (PKD1, PKD1L1, PKD1L2 or PKDL3). Interacts with PKD1. Interacts with PKD1L1; to form ciliary calcium channel. Interacts with PKD1L3, to form putative sour taste receptor. Interacts with RACK1; inhibits the channel activity possibly by impairing localization to the cell membrane.

Subcellular Location:
Cell projection ? cilium membrane; Multi-pass membrane protein

Tissue Specificity:
Expressed in adult heart, skeletal muscle, brain, spleen, testis, retina and liver. According to PubMed:9748274, expressed at high levels in fetal tissues, including kidney and liver, and down-regulated in adult tissues. According to PubMed:10602361, expressed in fetal brain, but not expressed in fetal lung, liver or kidney. Isoform 4 appears to be expressed only in transformed lymphoblasts.

Similarity:
Belongs to the polycystin family.

Database links:

Entrez Gene: 9033 Human

Entrez Gene: 329064 Mouse

SwissProt: Q9P0L9 Human

SwissProt: A2A259 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 亚洲高清91 | 成人黄网在线观看 | 萍萍的性荡生活 | 古典武侠激情亚洲精品一区 | 日韩视频一区二区在线 | 上锁的房间中国版免费 | 亚洲第一网站 | 在线观看免费网页欧美成 | 日日碰狠狠躁久久躁 | 人av在线| 一区二区在线播放视频 | 久久精品成人免费观看三 | 亚洲欧洲成人在线 | 日韩欧美成人一区二区三区 | free性丰满hd | 丁香花在线观看免费观看 | 日韩欧美在线播放 | 久久综合九色综合97伊人 | 国产三级日本三级在线播放 | 国产一二三四五 | 亚洲精品久久久久58 | 99在线国内在线视频22 | 日本一区二区高清不卡 | 成人毛片18女人毛片 | 日日摸夜添夜夜夜添高潮 | 亚洲AV无码专区亚洲AV网站 | 精品卡一卡二卡3卡高清乱码 | JAVASCRIPT中国免费 | 亚洲欧美不卡 | 在线视频观看免费视频18 | 免费人成视频在线观看视频 | 国产真实乱偷精品视频免 | 成人在线观看亚洲 | 理论片麻豆 | WWW射我里面在线观看 | 四级黄色毛片 | 亚洲色大情网站WWW 国产99视频精品免费观看6 | www在线免费 | 天堂久久一区二区三区 | 人人干日日操 | 亚洲色图狠狠爱 |